USMLE Step 2 CK Block 3 (2025) – Questions with Answers

Q81- 29-year-old male presented to the OPD with one month H/O depressed mood and fatigue. It takes him at least one hour to fall asleep at night. He complains of decreased work concentration and decreased interest in socializing. He no longer exercises. He has well controlled epilepsy with levetiracetam. On physical exam there is no abnormality. On mental status exam, he has a sad mood and is tearful briefly. There is no suicidal ideation, delusions or hallucinations. Which of the following is the most appropriate medication? A)Alprazolam B) Mirtazapine C) Aripiprazole D) Bupropion E) Buspirone

Q82- 55-year-old lady visited OPD for a health maintenance exam. She looks well. Medical history is unremarkable and there is no H/O medications. There is no family H/O any serious illness. On physical exam, even breast examination, there is no abnormality. Mammography shows a cluster of 20 pleomorphic microcalcifications in one cm area at the 3-o'clock position of the left breast. Which of the following is the most likely diagnosis? A) Adenosis B) Mastitis C) Fibroadenoma D) Fat necrosis E) Ductal carcinoma in situ

Q83- 13-year-old girl viisited OPD for a well-child examination. She looks well. There is no H/O serious illness and medications. Menarche has not yet occurred. For height she is at 30th percentil and 60th percentile for weight. Exam of the breasts shows no glandular tissue, the areolae follow the skin contours of the chest. Pubic hairs are absent. The remainder of the exam shows no abnormalities. Which of the following is the most appropriate next step in diagnosis ? A) No additional diagnostic steps are indicated B) To determine bone age, X-ray of the left hand and wrist C) Measurement of serum follicle-stimulating hormone and luteinizing hormone concentrations D) MRI of the brain E) Measurement of serum growth hormone and thyroxine concentrations

Q84- For ambulatory patients with several diagnoses a community created standard of care guidelines community's standard of care for patients with asthma is annual pulmonary function testing. Recent analysis of billing records from 1 clinic in the community reveals that 34% of pts with asthma at the clinic undergo pulmonary function testing. Enacting which of the following procedures is most likely to improve this clinic's adherence to the community's standard of care for asthamatic patients ? A) Pulmonary function testing of patients with asthma at each examination preceded by an exacerbation B) Pulmonary function testing of all patients examined for respiratory symptoms C) Placement of flyers in the clinic waiting room that remind patients with asthma to undergo annual pulmonary function testing D) Diagnosis-driven reminders in patient charts E) Annual chart reviews of patients with asthma and feedback to the physicians

Q85-A 12-year-old boy has joint pain, fever, and a new murmur after a sore throat. ASO titers are high. What is the most likely diagnosis? A) Infective endocarditis B) Rheumatic fever C) Kawasaki disease D) Juvenile idiopathic arthritis E) Viral myocarditis

Q86- 30-yr-old male is admitted to the ICU 3 hours after resection and anastomosis of a small-bowel injury and nephrectomy because of a right renal laceration sustained in a motor accident. He also has bilateral, minimally displaced pubic rami fractures. Intubation done and he is given mechanically ventilation. Morphine and propofol given. He responds only to painful stimuli. Pulse rate is 111/min, ventilatory rate is 13/min, and BP is 134/69 mm Hg. Abdomen is distended and soft, and incision is intact , clean, and dry. Since operation, urine output had been 41 mL/h and bloody. During the past hour, urine output is bloody and 5 mL. In addition to I/V administration of 0.9% saline. Which is the most appropriate next step in management? A) Ultrasonography of the bladder B) Transfusion of packed red blood cells C) Repeat surgical exploration of the abdomen D) CT scan of the abdomen and pelvis

Q87- 25-yr-old nulligravid lady presented to the OPD as she has been unable to conceive for the last one year. The couple have had regular unprotected intercourse during this time. The husband has no children. Prior to the attempt to conceive, wife was regularly using depot medroxyprogesterone. Menstural cycle is regular 28-day intervals with occasional mid-cycle abdominal pain previously diagnosed as mittelschmerz. At age 17 years she underwent appendicectomy and pelvic inflammatory disease at 19 years. At 21 years of age her cervical cytology showed a low-grade squamous intraepithelial lesion. On repeat cervical cytology 1 year later there are no abnormalities. Currently she is on a prenatal vitamin and occasional ibuprofen for midcycle abdominal pain. She is 168 cm (5 ft 6 in) tall and weighs 59 kg (130 lb). Her BMI is 21 kg/m2 . Vitals are normal. Physical exam reveals no abnormalities. Hysterosalpingography is performed, and x-rays obtained during the procedure is shown in the image below. Without treatment, which of the following is the most likely clinical course ? A) Successful pregnancy in the next year B) Recurrent spontaneous abortions C ) Hydatidiform mole D) Female factor infertility

Q88- 71-yr-old lady presented to the OPD as she experienced 3 episodes of rectal bleeding in the last four days. During each episode, she experienced sudden urge to have a bowel movement and passed bright red, bloody stool. There is no abdominal, chest, or rectal pain. no H/O palpitations, light-headedness, dizziness, or black stools. Her colonoscopy 8 years ago revealed no abnormalities. She has known H/O osteoarthritis for which she is taking daily ibuprofen. No H/O any other medications. She is 168 cm tall and weighs 68 kg. Her BMI is 25 kg/m2 . Temperature is 37.0°C, and R/R is 17/min. While sitting, her pulse is 81/min and BP is 131/75 mm Hg. At standing, her pulse rate is 87/min and BP is 126/74 mm Hg. On examination, she has mucous membranes. The abdomen is nondistended, soft, nontender. Rebound tenderness or guarding is absent. Bowel sounds are normal. Rectal examination shows no stool in the vault. There are no masses. Which of the following is the likely diagnosis? A) Ulcerative colitis B ) Chronic Gastritis C) Duodenal ulcer D) Diverticulosis E ) Colonic adenoma

Q89- 7-year-old boy is brought to the ER by the mother with acute onset one hour ago of severe rightsided lumbar pain and 3 episodes of emesis. The pain is sharp and makes him cry and double over. Medical and family history is unremarkable. There is no H/O medications. Temperature is 36.7°C, pulse rate is 151/min, R/R is 31/min, and BP is 111/70 mm Hg. He is in severe pain. Abdominal exam reveals right upper quadrant tenderness on palpation. Rest of the examination is normal. I/V morphine is administered and results in improvement in the pain management. Dipstick urinalysis is shown below in the image: Renal U/S shows severe right-sided hydronephrosis with moderate hydroureter to the bladder. Which of the following is the appropriate next step in the evaluation? A) Voiding cystourethrography B) Ultrasonography of the spinal column C) CT scan of the abdomen and pelvis D) Captopril renography E) Retrograde pyelography

Q90- 31-year-old lady is admitted due to a 2 year H/O intractable seizures. Her boyfriend, describes the seizures as bilateral limb shaking and moving her head from side to side, during these episodes she cries and closes her eyes. Episodes last for 15 to 20 minutes, and she is intermittently responsive during this period. She is given trials of phenytoin, oxcarbazepine, carbamazepine, gabapentin and divalproex. But no relief of her symptoms. Her current medications are and pregabalinzonisamide . She has a H/O childhood sexual and physical abuse. Vitals are normal. Her neurologic exam shows no focal findings. She undergoes long term video EEG monitoring, which reveals that her seizures are not associated with any EEG changes. Which is the most appropriate next step in her theraapy ? A) Epileptogenic focus surgical resection B) Psychoanalytic therapy C) Increasing pregabalin dosage D ) Hypnotic therapy E) Cognitive behavioral therapy

Q91- 41-yr-old male presented to the OPD during the summer due to a three day H/O fever, fatigue, sore throat, and diffuse muscle aches. No H/O sick contacts. His medical history is unremarkable and there is no H/O medications. He got influenza vaccine this year. 10 days back, he returned from Malaysia, where he enjoyed food and nightlife. Temperature is 38.8°C , pulse rate is 91/min, R/R is 16/min, and BP is 125/71 mm Hg. Rest of her examination is normal. Her laboratory studies are shown below : Monospot test result is negative. Which of the following is the most appropriate next step in diagnosis? A) Serum hepatitis B surface antigen testing B) HIV RNA polymerase chain reaction testing C) Hemagglutination inhibition assay D) Epstein-Barr virus serologic testing E) Cytomegalovirus serologic testing

Q92-A 16-year-old boy presents with fatigue and enlarged posterior cervical lymph nodes. Heterophile antibody test is positive. What is the most likely diagnosis? A) HIV infection B) Streptococcal pharyngitis C) Infectious mononucleosis D) CMV infection E) Toxoplasmosis

Q93- A 22-year-old woman presents to the gyne OPD with lower abdominal pain. There is no H/O any serious illness or medication. On examination there is cervical motion tenderness. Rest of her examination is normal. Her vital signs are within normal limits. What is the most appropriate initial therapy for her ? A) Azithromycin and ceftriaxone B) Metronidazole and ampicillin C) Doxycycline only D) Ciprofloxacin E) Vancomycin

Q94- A 30-year-old man presents with a target-shaped rash on his right leg.There is fever (38.8C) and malaise. Rest of her exam is unremarkable. What is the most likely diagnosis ? A) Cellulitis B) Erythema multiforme C) Erythema migrans D) Stevens-Johnson syndrome E) Tinea corporis

Q95- A 45-year-old woman presents to the OPD with a rash on her hands. She complains of arthralgia, and fatigue. Her lab results show elevated anti-dsDNA and low complement levels.est of the laboratory tests are within normal limits. What is the most likely diagnosis? A) Rheumatoid arthritis B) Systemic lupus erythematosus C) Dermatomyositis D) Scleroderma E) Sjogren's syndrome

Q96- A 50-year-old man presents to the clinic with sudden-onset dyspnea, chest pain, and hemoptysis. His D-dimer level is elevated. What is the next best step in management? A) Start heparin and perform a CT pulmonary angiogram B) Perform a ventilation-perfusion scan C) Order a chest X-ray D) Start antibiotics for suspected pneumonia E) Start warfarin therapy

Q97- A 28-year-old woman presents with irregular menstrual cycles, acne, and hirsutism. Her serum testosterone is elevated. What is the most likely diagnosis? A) Polycystic ovary syndrome B) Ovarian cancer C) Cushing's syndrome D) Hypothyroidism E) Hyperprolactinemia

Q98-A 45-year-old man presentsed to the OPD with a H/O nonproductive cough, weight loss, and night sweats. He has a history of tuberculosis. A chest X-ray shows a cavitary lesion in the upper lobe of both lungs. What is the most likely diagnosis? A) Primary Pulmonary tuberculosis B) Secondary pulmonary tuberculosis C) Pneumonia D) Bronchogenic carcinoma E) Sarcoidosis

Q99-A 35-year-old woman presents with right lower quadrant pain, fever, and nausea. She has a history of irregular periods. What is the most likely diagnosis? A) Acute appendicitis B) Ectopic pregnancy C) Pelvic inflammatory disease D. Ovarian torsion

Q100-A 68-year-old man with a history of hypertension and hyperlipidemia presents with a sudden onset of severe chest pain radiating to his back. His blood pressure is markedly elevated. What is the most likely diagnosis? A) Myocardial infarction B) Aortic dissection C) Pulmonary embolism D) Gastroesophageal reflux disease E) Costochondritis

Q101- A 26-year-old woman presents to the OPD with fever, flank pain, and dysuria. Urinalysis shows WBC casts. What is the most likely diagnosis? A) Cystitis B) Glomerulonephritis C) Pyelonephritis D) Interstitial nephritis E) Kidney stone

Q102- A 5-year-old boy presents with hematuria and periorbital edema after a diarrheal illness. Labs show thrombocytopenia, anemia, and renal failure. What is the most likely diagnosis? A) Post-streptococcal GN B) Minimal change disease C) Hemolytic uremic syndrome D) IgA nephropathy E) Lupus nephritis

Q103- A 60-year-old woman presents to the clinic with fatigue, abdominal pain, and weight loss. Her lab tests reveal an elevated alkaline phosphatase, and imaging shows a mass in the head of the pancreas. What is the most likely diagnosis? A) Acute pancreatitis B) Chronic pancreatitis C) Pancreatic adenocarcinoma D) Gallbladder adenocarcinoma E) Cystic fibrosis

Q104- A 30-year-old woman presented to the clinic with a H/O painless, hard, nonmobile mass in her left breast. She has no family history of breast cancer. What is the next best step in management ? A) Mammography B) Breast ultrasound C) Biopsy D) Fine needle aspiration E) Observation and follow-up

Q105- A 55-year-old man with a history of diabetes and hypertension presents with gradual-onset bilateral lower extremity edema and frothy urine. His urine protein to creatinine ratio is elevated. What is the most likely diagnosis? A) Chronic kidney disease B) Nephrotic syndrome C) Acute kidney injury D) Urinary tract infection E) Bladder cancer

Q106- A 40-year-old woman presents with severe lower abdominal pain and an absent period for the last two months. A urine pregnancy test is positive. What is the next best step in management? A) Serum beta-hCG levels B) Transvaginal ultrasound C) Pelvic exam D) Laparotomy E) MRI of the abdomen

Q107- 17-yr-old girl is brought to the clinic with a 3-day H/O diffuse abdominal pain, vomiting and fever. She is known case of cerebral palsy, severe scoliosis and situs inversus. She is on wheelchair for ambulation. During her previous visits, transferring her from the wheelchair to the examination table was time-consuming and was uncomfortable for her. Today, she appears uncomfortable. The physician decides to conduct the examination while she is sitting in her wheelchair. Her temperature is 101.0°F, pulse rate is 111/min, R/R 21/min, and BP is 110/51 mm Hg. On room air oxygen saturation is 100%. On examination there is mildly dry mucous membranes. The intern evaluated 4 previous patients today who had fever and vomiting, he diagnosed gastroenteritis in all four. Doctor attributes her increased pulse to mild dehydration and fever, and diagnoses her with gastroenteritis. He prescribes ondansetron and tells her to return if her symptoms worsens. 5 hours later, she is taken to the ER after her mother finds her listless and she is barely responsive. Temperature now is 102.0°F, pulse is 180/min, R/R 35/min, and BP of 70/50 mm Hg. On room air oxygen saturation of 96%. Abdominal CT shows volvulus, and emergency resection is done. Which of the following best describes the error that occurred ? A) Failure of systems B) Premature closure C) Non-preventable error D) Near missed E) Latent error

Q108- 43-yr-old lady presented to the clinic with a 2-month H/O episodes of light headedness and loss of consciousness for 10 secs. The episodes occur 2 to 3 times weekly while she is at work. She complains that her light-headedness resolves when she eats snacks. During this period, she also has had a 9-kg (20-lb) weight gain. She has no H/O any serious illness or no medications. She is 160 cm tall and weighs 72 kg. Her BMI is 28 kg/m2 . Vitals are normal. Physical exam shows no abnormalities. Serum glucose is 41 mg/dL, serum C peptide is 0.5 ng/mL (N=0.5–2.5), and serum insulin is 80 μIU/mL (N=5–20). Abdomen CT is most likely to show which of the following findings? A) No abnormality B) Vascular mass, neck of the pancreas C) Low-density pancreatic mass in the head, obstructing the main duct. D) Fluid-filled mass between the posterior aspect of the stomach and pancreas E) Duodenal mass with multiple liver mets.

Q109-A 12-month-old girl is brought to the office by her father because of a 3-day history of fever and mildly decreased appetite and activity. She has not had cough, vomiting, or diarrhea. She receives no medications. Vaccinations are up-to-date. She is at the 35th percentile for height, 50th percentile for weight, and 60th percentile for head circumference. Temperature is 39.2°C (102.6°F); other vital signs are within normal limits. Examination shows no other abnormalities. A catheter urine sample is obtained, and urinalysis shows 20–30 WBC/hpf and is positive for nitrites. Oral trimethoprim-sulfamethoxazole therapy is begun. The next day, urine culture grows greater than 100,000 colonies/mL of Escherichia coli that is susceptible to trimethoprimsulfamethoxazole. Which of the following is the most appropriate next step in management? A) Voiding cystourethrography B) Ultrasonography of the kidneys and bladder C) CT urography D) Clindamycin prophylaxis E) Ciprofloxacin prophylaxis

Q110- 17-yr-old boy comes to the ER because of moderate left knee pain with abrasions because of skateboarding collision. He has a H/O occasional injuries while skateboarding, including an injury to the same knee 5 months back. According to him his knee was fine until today's episode, and was fit and active. He has an EXT1 mutation, which is also present in his father. There is no H/O medications. Vitals are normal. On examination the anterolateral aspect of the left knee shows superficial abrasion. There is no effusion or instability in the knee, but tenderness is positive to palpation. He walks with a limp but is able to bear weight on the leg. The left knee X-ray shows two 1 × 2-cm bone polyps extending, medially and laterally, at the proximal tibia at the level of the closing physis. This is unchanged from an x-ray of the same knee done at his previous ER visit 6 months back. Which of the following is the most appropriate recommendation for activity and additional workup ? A) Recommendation for no weight bearing; no further workup needed B ) Recommendation to bear weight as tolerated; no further workup needed C) MRI of the knee and recommendation for no weight bearing D) Biopsy of the polyps and recommendation for no weight bearing E) Biopsy of the polyps and recommendation to bear weight as tolerated

Q111- 30 -yr-old lady, gravida 1, para 1, presented to the ER with one day H/O moderate pain in the Rt breast. 3 weeks ago, she had cesarean delivery of a healthy boy at term because of breech presentation. She is breast feeding, but the newborn latching is not proper on the right side. There is no H/O any serious illness. She is on acetaminophen for post OP pain and a prenatal vitamins. Temperature is 102.0°F. On examination right breast shows a 5 × 2-cm wedge-shaped area of erythema and tenderness. Left breast is normal. Abdominal examination shows a well healing incision. In addition to beginning antipyretic therapy, which of the following is the most appropriate next step in management? A) No further management is indicated B ) Fine-needle aspiration of the erythematous area C) Fluconazole therapy D) Dicloxacillin therapy E) Application of a breast binder on the right

Q112- 33-yr-old male presented to the OPD with two week H/O persistent nonproductive cough in short bursts. During the last week, he had bilateral chest pain with severe coughing. He has vomited several times after vigorous coughing. There is no shortness of breath or fever. 3 weeks back, he had sneezing, runny nose, and mild malaise that resolved spontaneously after one week. Toward the end of that episode, he noticed the onset of cough, which has since worsened. There is no H/O serious illness, and he only takes over-the-counter cough drops. Weekly drinks 24 to 36 oz of beer. No H/O smoking or use of other substances. He is sexually active with one male partne. They use condoms consistently. He is 173 cm tall and weighs 86 kg. His BMI is 29 kg/m2 . Temperature is 98.6°F, pulse is 70/min, R/R is 12/min, and BP is 121/80 mm Hg. On room air oxygen saturation of 98%. Patient coughs several times during the examination. There is no sinus tenderness to palpation. There is no cervical lymphadenopathy. The oropharynx looks normal. On auscultation lungs are clear. Ther are no abnormalities on cardiac examination. Which of the following is the most appropriate pharmacotherapy? A) Prednisone B) Omeprazole C) Levofloxacin D) Azithromycin E) Albuterol

Q113- 21-year-old male presented to the OPD at the end of the summer with a 2-month H/O generalized fatigue,malaise, and intermittent productive cough of whitish sputum, and decreased appetite. He has lost approximately 4 kg. He previously was on the college track team but now feels winded when he tries to go running. He has H/O childhood asthma. There is no H/O of medications. He does not smoke, drink alcohol, or use other substances. He identifies as African American. He was working at a lumber mill for the summer, feeding logs into a saw. He is 178 cm tall and weighs 77 kg. His BMI is 24 kg/m2 . Temperature is 37.7°C , pulse is 78/min, R/R is 21/min, and BP is 115/71 mm Hg. Bilaterally there are diffuse crackles. Rest of the examination shows no abnormality. X-ray chest shows a reticulonodular pattern, more prominent in the upper lung fields. Results of pulmonary function tests reveal a mixed obstructive and restrictive pattern. Which of the following is the most likely diagnosis ? A ) Silicosis B) Sarcoidosis C) Hypersensitivity pneumonitis D) Asthma recurrence E) Aspergillosis

Q114- 3-yr-old girl is brought to the OPD by parents for an initial assesment. Medical records show that she has a cleft palate and ventriculoseptal defects which are still not repaired. During the last 18 months, she experienced 2 episodes of pneumonia and at least ten episodes of otitis media treated with antibiotics. Her parents adopted her recently from China. She is at the 10th percentile for length and 5th percentile for weight. Vital are normal . Examination shows middle billateral ear effusions and a cleft palate. Lungs are clear on auscultation. On cardiac examination a grade 3/6 holosystolic murmur is heard. There is no hepatosplenomegaly. X-ray chest is normal. A complete blood count (CBC) is most likely to show which of the following leukocyte findings ? A) Neutrophilia B) Neutropenia C) Lymphopenia D) Lymphocytosis E) Eosinophilia

Q115- Patient Information : 56 years. Gender: Female, Race/Ethnicity: mixed race (White and Honduran). Clinical history of "I'm tired and I don't feel well." History of Present Illness: • fatigue and malaise for 3 months; tires quickly with physical activity • early satiety. Past Medical History: • 5-year history of hypertension • 5-year history of hyperlipidemia. Medications: • chlorthalidone • enalapril • atorvastatin Allergies: • no known drug allergies. The image below shows his labs. Which of the following is the most likely diagnosis? A) Monoclonal gammopathy of undetermined significance B) Chronic myeloid leukemia C) Chronic lymphocytic leukemia D) Acute myeloid leukemia E) Acute lymphocytic leukemia

Q116- 56-yr-old male presented to the OPD with his wife with a six month H/O restlessness during sleep. According to the wife he motions as if he were throwing or kicking a ball and punches the pillow at night; he has hit her twice. Recently, during his sleep he started talking and yelling expletives. Occasionally, he looks like “acting out” a dream; twice, he has awakened and could tell his wife what the dream was about. Otherwise, he is unaware of these episodes and feels well rested in the mornings. He has H/O constipation treated with polyethylene glycol. There is H/O medications. Vitals are normal. There are no abnormalities on examination. He is at the greatest risk for developing whhich of the following ? A) Parkinson disease B) Narcolepsy C) Cerebral infarction D) Amyotrophic lateral sclerosis E) Alzheimer disease

Q117- 29-yr-old male presents to the ER because of a four week H/O progressive shortness of breath and swelling of the lower extremities. During this period, there is shortness of breath during the night while lying down. there is six month H/o intermittent, moderate substernal chest pain and pressure while exercise. He has not had syncope. There is no H/O any serious illness and medications. Temperature is 37.0°C, pulse is 111/min, R/R is 25/min, and BP is 146/93 mm Hg. Examination shows severe, diffuse gingivitis. Crackles are heard halfway up the posterior lung bases bilaterally. On cardiac examination, there is a prominent S3. There is 3+ pitting edema of the lower extremities. On ECG there is sinus tachycardia. Which of the following is the most likely substance used? A) Toluene 109. B) Methamphetamine C) Methadone D) Heroin A) Cocaine

Q118- 66-yr-old lady presents to the OPD with a six month H/O progressive shortness of breath and one year H/O nonproductive cough. The shortness of breath initially occurred only at exertion but now also at rest. It get worsen when she lies down but is still present. Her symptoms have limited herself to travel internationally with the Peace Corps. There is no chest pain, chills, fever, or blood-tinged sputum. She is hypertensive, type 2 diabetes mellitus, and is a known case of major depressive disorder. She is onlisinopril, amlodipine, insulin glargine, and sertraline. She smoked 1 pack of cigarettes daily for the last 50 years. She takes one glass of wine on parties. Temperature is 37.2°C, pulse is 77/min, R/R of 17/min, and BP of 133/82 mm Hg. On room air, oxygen saturation is 94%. Jugular venous distention is absent. On pulmonary exam, end-expiratory wheezes are heard. There is prolonged expiratory phase. There are distant heart sounds. Which of the following is the most appropriate next step in her management? A) Pulmonary function testing B) PPD skin testing and chest x-ray C) Exercise stress testing D) Echocardiography E) CT scan of the chest

Q119- 44-yr-old lady is being prepared for discharge from the hospital after treatment for acute pancreatitis. For the past 12 hours she has tolerated oral fluids well. She has had 3 prior hospital admissions for pancreatitis. Medical history is remarkable for alcohol use disorder. The patient does not have secure housing. Which of the following recommendations is most likely to reduce this patient's risk for future hospital admissions? A) Placement in a women's shelter 59 B) Nutritional counseling C) Enrollment in a health insurance plan D) Abstinence from alcoholic beverages

Q120-. A 61-yr-old lady presents to the OPD for a health maintenance examination. She feels well. There is no H/o serious illness and medications. Vitals are normal. Observation of the tympanic membranes is limited because of cerumen filling both external auditory canals. External ears are normal. There are no other abnormalities. She says she hears well. Which of the following is the most appropriate next step in management? A) No further management is indicated at this time B) Recommendation for use of a ceruminolytic agent C) Recommendation for daily use of cotton swabs D) Manual removal of the cerumen by an otorhinolaryngologist E) Irrigation of the ear canals by the physician

USMLE Step 2 CK Block 3 (2025) – Questions & Review

Preparing for the USMLE Step 2 CK 2025? This page focuses on Block 3 of the exam, offering detailed insights into the types of questions you’ll face and how to approach them. Step 2 CK emphasizes clinical knowledge and the application of medical understanding in real-life patient care scenarios. Block 3 typically includes a mix of internal medicine, pediatrics, surgery, psychiatry, and OB-GYN questions.

Each question tests your ability to evaluate clinical cases, prioritize differential diagnoses, and choose appropriate investigations or treatments. To succeed, it’s crucial to focus on high-yield topics, time management, and evidence-based reasoning.

Our review includes sample questions with detailed explanations, tips for test-day strategy, and updates aligned with the latest NBME guidelines. Whether you’re using UWorld, NBME forms, or other question banks, this block-specific breakdown will help you pinpoint weaknesses and improve accuracy.

Start your revision strong with our expert-curated content.

5/5 - (4 votes)

USMLE STEP 2 CK2 BLOCK 3 2025

USMLE Step 2 CK Block 3 (2025) – Questions & Review

About us

Contact us

Privacy policy

Terms and condition

Blog

Physiology Mcqs

Anatomy Mcqs

Nutrition Mcqs

Pathology Mcqs

Community medicine Mcqs

MDCAT Test Preparation

Saudi Medical Licensing Exam

US Medical Licensing Examination

MRCP Part 1 Exam UK/Ireland

Case Based Learning